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Disrupting Interleukin 12 Improves Microvascular Endothelial Function in Type 2 Diabetes Through ER Stress CHOP and Oxidative Stress Mechanisms

PURPOSE: Vascular endothelial dysfunction is well established in type 2 diabetes. Interleukin-12 (IL-12) and endoplasmic reticulum (ER) stress are up-regulated in type 2 diabetic patients and animal models of type 2 diabetes. However, the role and underlying mechanisms of IL-12 and the ER stress CHO...

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Detalles Bibliográficos
Autores principales: Radwan, Eman, Belmadani, Souad, Matrougui, Khalid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440700/
https://www.ncbi.nlm.nih.gov/pubmed/36065460
http://dx.doi.org/10.2147/DMSO.S369488