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Regulation of the Keap1-Nrf2 Signaling Axis by Glycyrrhetinic Acid Promoted Oxidative Stress-Induced H(9)C(2) Cell Apoptosis

Excessive reactive oxygen species (ROS) could interfere with the physiological capacities of H(9)C(2) cells and cause cardiomyocyte apoptosis. Glycyrrhetinic acid (GA), one of the main medicinal component of Glycyrrhetinic Radix et Rhizoma, shows toxic and adverse side effects in the clinic setting....

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Detalles Bibliográficos
Autores principales: Jiang, Zhangyu, Wang, Yanqing, Xi, Xiuli, Cai, Weibin, Liu, Changhui, Ye, Ran, Yang, Liu, Zhang, Song, Zhang, Rong, Xu, Qin, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440773/
https://www.ncbi.nlm.nih.gov/pubmed/36065263
http://dx.doi.org/10.1155/2022/2875558