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TRPV1 Modulator Ameliorates Alzheimer-Like Amyloid-β Neuropathology via Akt/Gsk3β-Mediated Nrf2 Activation in the Neuro-2a/APP Cell Model

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder for which there is no effective therapeutic strategy. PcActx peptide from the transcriptome of zoantharian Palythoa caribaeorum has recently been identified and verified as a novel antagonist of transient rece...

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Detalles Bibliográficos
Autores principales: Wang, Xiufen, Bian, Yaqi, Wong, Clarence Tsun Ting, Lu, Jia-Hong, Lee, Simon Ming-Yuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440841/
https://www.ncbi.nlm.nih.gov/pubmed/36065437
http://dx.doi.org/10.1155/2022/1544244