Pharmacodynamic effect of bempedoic acid and statin combinations: predictions from a dose–response model

AIMS: Many patients are unable to achieve guideline-recommended LDL cholesterol (LDL-C) targets, despite taking maximally tolerated lipid-lowering therapy. Bempedoic acid, a competitive inhibitor of ATP citrate lyase, significantly lowers LDL-C with or without background statin therapy in diverse po...

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Detalles Bibliográficos
Autores principales: Jadhav, Satyawan B, Crass, Ryan L, Chapel, Sunny, Kerschnitzki, Michael, Sasiela, William J, Emery, Maurice G, Amore, Benny M, Barrett, P Hugh R, Watts, Gerald F, Catapano, Alberico L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440868/
https://www.ncbi.nlm.nih.gov/pubmed/34448822
http://dx.doi.org/10.1093/ehjcvp/pvab064

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440868/
https://www.ncbi.nlm.nih.gov/pubmed/34448822
http://dx.doi.org/10.1093/ehjcvp/pvab064

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