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SMYD3 promotes aerobic glycolysis in diffuse large B-cell lymphoma via H3K4me3-mediated PKM2 transcription

Genetic abnormalities in histone methyltransferases (HMTs) frequently occur in diffuse large B-cell lymphoma (DLBCL) and are related to its progression. SET and MYND domain containing 3 (SMYD3) is an HMT that is upregulated in various tumors and promotes their malignancy. However, to the best of our...

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Detalles Bibliográficos
Autores principales: Tian, Tian, Li, Jiwei, Shi, Di, Zeng, Yupeng, Yu, Baohua, Li, Xiaoqiu, Wei, Ping, Zhou, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440895/
https://www.ncbi.nlm.nih.gov/pubmed/36057625
http://dx.doi.org/10.1038/s41419-022-05208-7