Cargando…

Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis

Activation of multiple inflammasomes in monocytes/macrophages is associated with the pathogenesis of systemic lupus erythematosus (SLE). Gasdermin D (GSDMD)-mediated pyroptosis, a common consequence of multiple activated inflammasomes, is a programmed cell death with strong inflammatory responses. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhuang, Lili, Luo, Xiaoqing, Wu, Shufan, Lin, Zhangmei, Zhang, Yanan, Zhai, Zeqing, Yang, Fangyuan, Li, Yehao, Zhuang, Jian, Luo, Guihu, Xu, Wenchao, He, Yi, Sun, Erwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440918/
https://www.ncbi.nlm.nih.gov/pubmed/36057687
http://dx.doi.org/10.1038/s41420-022-01167-2