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Disulfiram alleviates pristane-induced lupus via inhibiting GSDMD-mediated pyroptosis
Activation of multiple inflammasomes in monocytes/macrophages is associated with the pathogenesis of systemic lupus erythematosus (SLE). Gasdermin D (GSDMD)-mediated pyroptosis, a common consequence of multiple activated inflammasomes, is a programmed cell death with strong inflammatory responses. T...
Autores principales: | Zhuang, Lili, Luo, Xiaoqing, Wu, Shufan, Lin, Zhangmei, Zhang, Yanan, Zhai, Zeqing, Yang, Fangyuan, Li, Yehao, Zhuang, Jian, Luo, Guihu, Xu, Wenchao, He, Yi, Sun, Erwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440918/ https://www.ncbi.nlm.nih.gov/pubmed/36057687 http://dx.doi.org/10.1038/s41420-022-01167-2 |
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