Kaiso phosphorylation at threonine 606 leads to its accumulation in the cytoplasm, reducing its transcriptional repression of the tumour suppressor CDH1

It is well known that the Kaiso protein (encoded by the ZBTB33 gene) is a transcription factor, and Kaiso–P120ctn [P120 catenin (CTNND1)] interaction increases the translocation of Kaiso from the nucleus into the cytoplasm. However, the regulatory mechanisms of Kaiso compartmentalisation are far fro...

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Detalles Bibliográficos
Autores principales: Tian, Wei, Yuan, Hongfan, Qin, Sisi, Liu, Wensu, Zhang, Baozhen, Gu, Liankun, Zhou, Jing, Deng, Dajun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441001/
https://www.ncbi.nlm.nih.gov/pubmed/35851744
http://dx.doi.org/10.1002/1878-0261.13292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441001/
https://www.ncbi.nlm.nih.gov/pubmed/35851744
http://dx.doi.org/10.1002/1878-0261.13292

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