KSR induces RAS‐independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors

The kinase suppressor of rat sarcoma (RAS) proteins (KSR1 and KSR2) have long been considered as scaffolding proteins required for optimal mitogen‐activated protein kinase (MAPK) pathway signalling. However, recent evidence suggests that they play a more complex role within this pathway. Here, we de...

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Detalles Bibliográficos
Autores principales: Paniagua, Guillem, Jacob, Harrys K.C., Brehey, Oksana, García‐Alonso, Sara, Lechuga, Carmen G., Pons, Tirso, Musteanu, Monica, Guerra, Carmen, Drosten, Matthias, Barbacid, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441002/
https://www.ncbi.nlm.nih.gov/pubmed/35313064
http://dx.doi.org/10.1002/1878-0261.13213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441002/
https://www.ncbi.nlm.nih.gov/pubmed/35313064
http://dx.doi.org/10.1002/1878-0261.13213

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