Radiated glioblastoma cell-derived exosomal circ_0012381 induce M2 polarization of microglia to promote the growth of glioblastoma by CCL2/CCR2 axis

BACKGROUND: Radiotherapy is the primary therapeutic option for glioblastoma. Some studies proved that radiotherapy increased the release of exosomes from cells. The mechanism by which these exosomes modify the phenotype of microglia in the tumor microenvironment to further determine the fate of irra...

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Detalles Bibliográficos
Autores principales: Zhang, Chunzhi, Zhou, Yuan, Gao, Ya, Zhu, Ze, Zeng, Xianliang, Liang, Weizi, Sun, Songwei, Chen, Xiuli, Wang, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441045/
https://www.ncbi.nlm.nih.gov/pubmed/36058942
http://dx.doi.org/10.1186/s12967-022-03607-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441045/
https://www.ncbi.nlm.nih.gov/pubmed/36058942
http://dx.doi.org/10.1186/s12967-022-03607-0

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