Spermidine protects against acute kidney injury by modulating macrophage NLRP3 inflammasome activation and mitochondrial respiration in an eIF5A hypusination-related pathway

BACKGROUND: Acute kidney injury (AKI) is still a critical problem in clinical practice, with a heavy burden for national health system around the world. It is notable that sepsis is the predominant cause of AKI for patients in the intensive care unit and the mortality remains considerably high. The...

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Detalles Bibliográficos
Autores principales: Li, Xianzhi, Zhou, Xiaojun, Liu, Xigao, Li, Xiaoyun, Jiang, Xianzhou, Shi, Benkang, Wang, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441050/
https://www.ncbi.nlm.nih.gov/pubmed/36058905
http://dx.doi.org/10.1186/s10020-022-00533-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441050/
https://www.ncbi.nlm.nih.gov/pubmed/36058905
http://dx.doi.org/10.1186/s10020-022-00533-1

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