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Novel eIF4A1 inhibitors with anti‐tumor activity in lymphoma

BACKGROUND: Deregulated translation initiation is implicated extensively in cancer initiation and progression. It is actively pursued as a viable target that circumvents the dependency on oncogenic signaling, a significant factor in current strategies. Eukaryotic translation initiation factor (eIF)...

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Detalles Bibliográficos
Autores principales: Kayastha, Forum, Herrington, Noah B., Kapadia, Bandish, Roychowdhury, Anirban, Nanaji, Nahid, Kellogg, Glen E., Gartenhaus, Ronald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441068/
https://www.ncbi.nlm.nih.gov/pubmed/36058921
http://dx.doi.org/10.1186/s10020-022-00534-0