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Histone Deacetylase Inhibitor I3 Induces the Differentiation of Acute Myeloid Leukemia Cells with t (8; 21) or MLL Gene Translocation and Leukemic Stem-Like Cells

Acute myeloid leukemia (AML) is a heterogeneous disorder characterized by the clonal expansion and differentiation arrest of leukemic cells in peripheral blood and bone marrow. Though the treatment using cytarabine-based protocol for AML patients with t (8; 21) translocation has improved the 5-year...

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Detalles Bibliográficos
Autores principales: Zhao, Mengjie, Duan, Yu, Wang, Jiangyun, Liu, Yong, Zhao, Yao, Wang, Haihua, Zhang, Lei, Chen, Zhe-Sheng, Hu, Zhenbo, Wei, Liuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441378/
https://www.ncbi.nlm.nih.gov/pubmed/36072977
http://dx.doi.org/10.1155/2022/3345536