Silibinin-modified Hydroxyapatite coating promotes the osseointegration of titanium rods by activation SIRT1/SOD2 signaling pathway in diabetic rats

The purpose of this study is to investigate the role of Silibinin (SIL)-modified Hydroxyapatite coating on osseointegration in diabetes in vivo and in vitro and explore the mechanism of osteogenic differentiation of MC3T3-E1. RT-qPCR, Immunofluorescence, and Western blot were used to measure the exp...

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Detalles Bibliográficos
Autores principales: Tao, Zhou-Shan, Wang, Hai-Sheng, Li, Tian-Lin, Wei, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Delivery Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441422/
https://www.ncbi.nlm.nih.gov/pubmed/36057883
http://dx.doi.org/10.1007/s10856-022-06684-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441422/
https://www.ncbi.nlm.nih.gov/pubmed/36057883
http://dx.doi.org/10.1007/s10856-022-06684-1

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