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CYP2C19 loss-of-function alleles predicts clinical outcomes in East Asian patients with acute myocardial infarction undergoing percutaneous coronary intervention and stenting receiving clopidogrel

BACKGROUND: CYP2C19 loss-of-function (LOF) alleles reduce the effectiveness of clopidogrel and are associated with high rates of clinical events in patients undergoing percutaneous coronary intervention (PCI) and stenting in Northeast Asians. However, the prevalence and influence of CYP2C19 LOF alle...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Wei, Liao, Yi-Ju, Chang, Wei-Chun, Hsiao, Tzu-Hung, Lin, Ching-Heng, Hsu, Chiann-Yi, Liu, Tsun-Jui, Lee, Wen-Lieng, Chen, Yi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441652/
https://www.ncbi.nlm.nih.gov/pubmed/36072879
http://dx.doi.org/10.3389/fcvm.2022.994184