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The CD63 homologs, Tsp42Ee and Tsp42Eg, restrict endocytosis and promote neurotransmission through differential regulation of synaptic vesicle pools

The Tetraspanin (Tsp), CD63, is a transmembrane component of late endosomes and facilitates vesicular trafficking through endosomal pathways. Despite being widely expressed in the human brain and localized to late endosomes, CD63's role in regulating endo- and exocytic cycling at the synapse ha...

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Detalles Bibliográficos
Autores principales: Hendricks, Emily L., Smith, Ireland R., Prates, Bruna, Barmaleki, Fatemeh, Liebl, Faith L. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441712/
https://www.ncbi.nlm.nih.gov/pubmed/36072568
http://dx.doi.org/10.3389/fncel.2022.957232