Activation of lactate receptor HCAR1 down-modulates neuronal activity in rodent and human brain tissue

Lactate can be used by neurons as an energy substrate to support their activity. Evidence suggests that lactate also acts on a metabotropic receptor called HCAR1, first described in the adipose tissue. Whether HCAR1 also modulates neuronal circuits remains unclear. In this study, using qRT-PCR, we s...

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Detalles Bibliográficos
Autores principales: Briquet, Marc, Rocher, Anne-Bérengère, Alessandri, Maxime, Rosenberg, Nadia, de Castro Abrantes, Haissa, Wellbourne-Wood, Joel, Schmuziger, Céline, Ginet, Vanessa, Puyal, Julien, Pralong, Etienne, Daniel, Roy Thomas, Offermanns, Stefan, Chatton, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441721/
https://www.ncbi.nlm.nih.gov/pubmed/35240875
http://dx.doi.org/10.1177/0271678X221080324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441721/
https://www.ncbi.nlm.nih.gov/pubmed/35240875
http://dx.doi.org/10.1177/0271678X221080324

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