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Dynamic Mass Balance Modeling for Chemical Distribution Over Time in In Vitro Systems With Repeated Dosing

As toxicologists and risk assessors move away from animal testing and more toward using in vitro models and biological modeling, it is necessary to produce tools to quantify the chemical distribution within the in vitro environment prior to extrapolating in vitro concentrations to human equivalent d...

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Detalles Bibliográficos
Autores principales: Bloch, Sherri, Arnot, Jon A., Kramer, Nynke I., Armitage, James M., Verner, Marc-André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441784/
https://www.ncbi.nlm.nih.gov/pubmed/36071822
http://dx.doi.org/10.3389/ftox.2022.911128