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Dynamic Mass Balance Modeling for Chemical Distribution Over Time in In Vitro Systems With Repeated Dosing
As toxicologists and risk assessors move away from animal testing and more toward using in vitro models and biological modeling, it is necessary to produce tools to quantify the chemical distribution within the in vitro environment prior to extrapolating in vitro concentrations to human equivalent d...
Autores principales: | Bloch, Sherri, Arnot, Jon A., Kramer, Nynke I., Armitage, James M., Verner, Marc-André |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441784/ https://www.ncbi.nlm.nih.gov/pubmed/36071822 http://dx.doi.org/10.3389/ftox.2022.911128 |
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