Nicotinamide-riboside shifts the differentiation of human primary white adipocytes to beige adipocytes impacting substrate preference and uncoupling respiration through SIRT1 activation and mitochondria-derived reactive species production

Beige adipocytes play key roles in organismal energy and metabolic balance. In this study, we assessed whether the supplementation of human white adipocytes, differentiated from human adipose tissue-derived stem cells, with nicotinamide riboside (NR), a potent NAD + precursor, can shift differentiat...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagy, Lilla, Rauch, Boglárka, Szerafin, Tamás, Uray, Karen, Tóth, Attila, Bai, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441796/
https://www.ncbi.nlm.nih.gov/pubmed/36072335
http://dx.doi.org/10.3389/fcell.2022.979330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441796/
https://www.ncbi.nlm.nih.gov/pubmed/36072335
http://dx.doi.org/10.3389/fcell.2022.979330

Ejemplares similares