Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen

Although the current hepatitis B (HB) vaccine comprising small-HBs antigen (Ag) is potent and safe, attenuated prophylaxis against hepatitis B virus (HBV) with vaccine-escape mutations (VEMs) has been reported. We investigate an HB vaccine consisting of large-HBsAg that overcomes the shortcomings of...

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Detalles Bibliográficos
Autores principales: Washizaki, Ayaka, Murayama, Asako, Murata, Megumi, Kiyohara, Tomoko, Yato, Keigo, Yamada, Norie, Aly, Hussein Hassan, Tanaka, Tomohisa, Moriishi, Kohji, Nishitsuji, Hironori, Shimotohno, Kunitada, Goh, Yasumasa, Ishii, Ken J., Yotsuyanagi, Hiroshi, Muramatsu, Masamichi, Ishii, Koji, Takahashi, Yoshimasa, Suzuki, Ryosuke, Akari, Hirofumi, Kato, Takanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441830/
https://www.ncbi.nlm.nih.gov/pubmed/36064848
http://dx.doi.org/10.1038/s41467-022-32910-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441830/
https://www.ncbi.nlm.nih.gov/pubmed/36064848
http://dx.doi.org/10.1038/s41467-022-32910-z

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