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HupB, a nucleoid-associated protein, is critical for survival of Mycobacterium tuberculosis under host-mediated stresses and for enhanced tolerance to key first-line antibiotics

To survive and establish its niche, Mycobacterium tuberculosis (Mtb) engages in a steady battle against an array of host defenses and a barrage of antibiotics. Here, we demonstrate that Mtb employs HupB, a nucleoid-associated protein (NAP) as its key player to simultaneously battle and survive in th...

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Detalles Bibliográficos
Autores principales: Singh, Niti, Sharma, Nishant, Singh, Padam, Pandey, Manitosh, Ilyas, Mohd, Sisodiya, Lovely, Choudhury, Tejaswini, Gosain, Tannu Priya, Singh, Ramandeep, Atmakuri, Krishnamohan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441915/
https://www.ncbi.nlm.nih.gov/pubmed/36071978
http://dx.doi.org/10.3389/fmicb.2022.937970