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New perspectives on the regulation of germinal center reaction via αvβ8- mediated activation of TGFβ
Transforming growth factor-β (TGFβ) is a long-known modulator of immune responses but has seemingly contradictory effects on B cells. Among cytokines, TGFβ has the particularity of being produced and secreted in a latent form and must be activated before it can bind to its receptor and induce signal...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441935/ https://www.ncbi.nlm.nih.gov/pubmed/36072589 http://dx.doi.org/10.3389/fimmu.2022.942468 |