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Strategies to induce natural killer cell tolerance in xenotransplantation

Eliminating major xenoantigens in pig cells has drastically reduced human antibody-mediated hyperacute xenograft rejection (HXR). Despite these advancements, acute xenograft rejection (AXR) remains one of the major obstacles to clinical xenotransplantation, mediated by innate immune cells, including...

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Detalles Bibliográficos
Autores principales: Lopez, Kevin J., Cross-Najafi, Arthur A., Farag, Kristine, Obando, Benjamin, Thadasina, Deepthi, Isidan, Abdulkadir, Park, Yujin, Zhang, Wenjun, Ekser, Burcin, Li, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441937/
https://www.ncbi.nlm.nih.gov/pubmed/36072599
http://dx.doi.org/10.3389/fimmu.2022.941880