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Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitis

Liver fibrosis is one main histological characteristic of nonalcoholic steatohepatitis (NASH), a disease paralleling a worldwide surge in metabolic syndromes with no approved therapies. The role of the gut microbiota in NASH pathogenesis has not been thoroughly illustrated, especially how the gut mi...

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Detalles Bibliográficos
Autores principales: Zhou, Dengcheng, Zhang, Jing, Xiao, Chengju, Mo, Chunheng, Ding, Bi-Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441952/
https://www.ncbi.nlm.nih.gov/pubmed/36072588
http://dx.doi.org/10.3389/fimmu.2022.964477