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A single molecule investigation of i-motif stability, folding intermediates, and potential as in-situ pH sensor

We present a collection of single molecule work on the i-motif structure formed by the human telomeric sequence. Even though it was largely ignored in earlier years of its discovery due to its modest stability and requirement for low pH levels (pH < 6.5), the i-motif has been attracting more atte...

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Detalles Bibliográficos
Autores principales: Mustafa, Golam, Gyawali, Prabesh, Taylor, Jacob A., Maleki, Parastoo, Nunez, Marlon V., Guntrum, Michael C., Shiekh, Sajad, Balci, Hamza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9441956/
https://www.ncbi.nlm.nih.gov/pubmed/36072435
http://dx.doi.org/10.3389/fmolb.2022.977113