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Aberrant orbitofrontal cortical activation interferes with encoding of Pavlovian fear conditioning

Obsessive-compulsive disorder (OCD) patients were usually found with the hyper-activation of the orbitofrontal cortex (OFC) and a deficit in fear extinction learning. The OFC can be subdivided into the lateral OFC (lOFC) and the medial OFC (mOFC). Previous studies have suggested that both subregions...

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Detalles Bibliográficos
Autores principales: Sun, Chung-Fu, Chang, Chun-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442050/
https://www.ncbi.nlm.nih.gov/pubmed/36072088
http://dx.doi.org/10.3389/fnbeh.2022.981041