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CTCF shapes chromatin structure and gene expression in health and disease

CCCTC‐binding factor (CTCF) is an eleven zinc finger (ZF), multivalent transcriptional regulator, that recognizes numerous motifs thanks to the deployment of distinct combinations of its ZFs. The great majority of the ~50,000 genomic locations bound by the CTCF protein in a given cell type is interg...

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Detalles Bibliográficos
Autores principales: Dehingia, Bondita, Milewska, Małgorzata, Janowski, Marcin, Pękowska, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442299/
https://www.ncbi.nlm.nih.gov/pubmed/35993175
http://dx.doi.org/10.15252/embr.202255146