hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK and BRD4

The P‐TEFb complex promotes transcription elongation by releasing paused RNA polymerase II. P‐TEFb itself is known to be inactivated through binding to the non‐coding RNA 7SK but there is only limited information about mechanisms regulating their association. Here, we show that cells deficient in th...

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Detalles Bibliográficos
Autores principales: Ji, Changhe, Deng, Chunchu, Antor, Katharina, Bischler, Thorsten, Schneider, Cornelius, Fischer, Utz, Sendtner, Michael, Briese, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442301/
https://www.ncbi.nlm.nih.gov/pubmed/35856391
http://dx.doi.org/10.15252/embr.202255432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442301/
https://www.ncbi.nlm.nih.gov/pubmed/35856391
http://dx.doi.org/10.15252/embr.202255432

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