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hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK and BRD4
The P‐TEFb complex promotes transcription elongation by releasing paused RNA polymerase II. P‐TEFb itself is known to be inactivated through binding to the non‐coding RNA 7SK but there is only limited information about mechanisms regulating their association. Here, we show that cells deficient in th...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442301/ https://www.ncbi.nlm.nih.gov/pubmed/35856391 http://dx.doi.org/10.15252/embr.202255432 |