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IL‐21 has a critical role in establishing germinal centers by amplifying early B cell proliferation

The proliferation and differentiation of antigen‐specific B cells, including the generation of germinal centers (GC), are prerequisites for long‐lasting, antibody‐mediated immune protection. Affinity for antigen determines B cell recruitment, proliferation, differentiation, and competitiveness in th...

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Detalles Bibliográficos
Autores principales: Dvorscek, Alexandra R, McKenzie, Craig I, Robinson, Marcus J, Ding, Zhoujie, Pitt, Catherine, O'Donnell, Kristy, Zotos, Dimitra, Brink, Robert, Tarlinton, David M, Quast, Isaak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442303/
https://www.ncbi.nlm.nih.gov/pubmed/35801309
http://dx.doi.org/10.15252/embr.202254677