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Transient upregulation of IRF1 during exit from naive pluripotency confers viral protection

Stem cells intrinsically express a subset of genes which are normally associated with interferon stimulation and the innate immune response. However, the expression of these interferon‐stimulated genes (ISG) in stem cells is independent from external stimuli such as viral infection. Here, we show th...

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Detalles Bibliográficos
Autores principales: Romeike, Merrit, Spach, Stephanie, Huber, Marie, Feng, Songjie, Vainorius, Gintautas, Elling, Ulrich, Versteeg, Gjis A, Buecker, Christa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442322/
https://www.ncbi.nlm.nih.gov/pubmed/35852463
http://dx.doi.org/10.15252/embr.202255375