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Transient rapamycin treatment during developmental stage extends lifespan in Mus musculus and Drosophila melanogaster

Lifespan is determined by complex and tangled mechanisms that are largely unknown. The early postnatal stage has been proposed to play a role in lifespan, but its contribution is still controversial. Here, we show that a short rapamycin treatment during early life can prolong lifespan in Mus musculu...

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Detalles Bibliográficos
Autores principales: Aiello, Giuseppe, Sabino, Cosimo, Pernici, Davide, Audano, Matteo, Antonica, Francesco, Gianesello, Matteo, Ballabio, Claudio, Quattrone, Alessandro, Mitro, Nico, Romanel, Alessandro, Soldano, Alessia, Tiberi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442325/
https://www.ncbi.nlm.nih.gov/pubmed/35796299
http://dx.doi.org/10.15252/embr.202255299