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Extracellular loop 2 of G protein–coupled olfactory receptors is critical for odorant recognition

G protein–coupled olfactory receptors (ORs) enable us to detect innumerous odorants. They are also ectopically expressed in nonolfactory tissues and emerging as attractive drug targets. ORs can be promiscuous or highly specific, which is part of a larger mechanism for odor discrimination. Here, we d...

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Detalles Bibliográficos
Autores principales: Yu, Yiqun, Ma, Zhenjie, Pacalon, Jody, Xu, Lun, Li, Weihao, Belloir, Christine, Topin, Jeremie, Briand, Loïc, Golebiowski, Jérôme, Cong, Xiaojing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442423/
https://www.ncbi.nlm.nih.gov/pubmed/35926708
http://dx.doi.org/10.1016/j.jbc.2022.102331