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Effect of CD4+ T cell count on treatment-emergent adverse events among patients with and without HIV receiving immunotherapy for advanced cancer

BACKGROUND: The Food and Drug Administration recommends that people living with HIV (PWH) with a CD4+ T cell count (CD4) ≥350 cells/µL may be eligible for any cancer clinical trial, but there is reluctance to enter patients with lower CD4 counts into cancer studies, including immune checkpoint inhib...

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Detalles Bibliográficos
Autores principales: Odeny, Thomas A, Lurain, Kathryn, Strauss, Julius, Fling, Steven P, Sharon, Elad, Wright, Anna, Martinez-Picado, Javier, Moran, Teresa, Gulley, James L, Gonzalez-Cao, Maria, Uldrick, Thomas S, Yarchoan, Robert, Ramaswami, Ramya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442492/
https://www.ncbi.nlm.nih.gov/pubmed/37935055
http://dx.doi.org/10.1136/jitc-2022-005128