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Interpreting alignment-free sequence comparison: what makes a score a good score?
Alignment-free methods are alternatives to alignment-based methods when searching sequence data sets. The output from an alignment-free sequence comparison is a similarity score, the interpretation of which is not straightforward. We propose objective functions to interpret and calibrate outputs fro...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442500/ https://www.ncbi.nlm.nih.gov/pubmed/36071721 http://dx.doi.org/10.1093/nargab/lqac062 |