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Interpreting alignment-free sequence comparison: what makes a score a good score?

Alignment-free methods are alternatives to alignment-based methods when searching sequence data sets. The output from an alignment-free sequence comparison is a similarity score, the interpretation of which is not straightforward. We propose objective functions to interpret and calibrate outputs fro...

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Detalles Bibliográficos
Autores principales: Swain, Martin T, Vickers, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442500/
https://www.ncbi.nlm.nih.gov/pubmed/36071721
http://dx.doi.org/10.1093/nargab/lqac062

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