Silencing of Angiopoietin-Like Protein 4 (Angptl4) Decreases Inflammation, Extracellular Matrix Degradation, and Apoptosis in Osteoarthritis via the Sirtuin 1/NF-κB Pathway

Osteoarthritis (OA) is a frequently observed condition in aged people. OA cartilage is characterized by chondrocyte apoptosis, chondrocyte inflammation, and hyperactive catabolism of extracellular matrix. However, the specific molecular mechanisms remain unclear. Recent data has shown that Angptl4,...

Descripción completa

Detalles Bibliográficos
Autores principales: Jia, Chao, Li, Xiucui, Pan, Jun, Ma, Haiwei, Wu, Dengying, Lu, Hongwei, Wang, Wei, Zhang, Xutong, Yi, Xianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442503/
https://www.ncbi.nlm.nih.gov/pubmed/36071864
http://dx.doi.org/10.1155/2022/1135827

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442503/
https://www.ncbi.nlm.nih.gov/pubmed/36071864
http://dx.doi.org/10.1155/2022/1135827

Ejemplares similares