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Sex-differential RXRα gene methylation effects on mRNA and protein expression in umbilical cord of the offspring rat exposed to maternal obesity

Maternal obesity (MO) induces negative consequences in the offspring development. Adiposity phenotype is associated with maternal diet at early pregnancy and DNA methylation marks in the RXRα promotor at birth. Glucocorticoids play an important role in the regulation of metabolism through the activa...

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Detalles Bibliográficos
Autores principales: Chavira-Suárez, Erika, Reyes-Castro, Luis Antonio, López-Tenorio, Itzel Ivonn, Vargas-Hernández, Lilia, Rodríguez-González, Guadalupe L., Chavira, Roberto, Zárate-Segura, Paola, Domínguez-López, Aaron, Vadillo-Ortega, Felipe, Zambrano, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442673/
https://www.ncbi.nlm.nih.gov/pubmed/36072345
http://dx.doi.org/10.3389/fcell.2022.892315