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Glycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells

[Image: see text] Driven by the lack of targeted therapies, triple-negative breast cancers (TNBCs) have the worst overall survival of all breast cancer subtypes. Considering that cell surface proteins are favorable drug targets and are predominantly glycosylated, glycoproteome profiling has signific...

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Detalles Bibliográficos
Autores principales: Kuhlmann, Laura, Govindarajan, Meinusha, Mejia-Guerrero, Salvador, Ignatchenko, Vladimir, Liu, Lydia Y., Grünwald, Barbara T., Cruickshank, Jennifer, Berman, Hal, Khokha, Rama, Kislinger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9442790/
https://www.ncbi.nlm.nih.gov/pubmed/35981243
http://dx.doi.org/10.1021/acs.jproteome.2c00332