TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination

BACKGROUND: Diabetic retinopathy (DR) as a severe diabetic complication contributes to blindness. The increased permeability of retinal capillary endothelial cells (RCECs) as well as the production of inflammatory markers are closely related to DR occurrence. We recently revealed that TRIM46 promote...

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Detalles Bibliográficos
Autores principales: Shen, Hangqi, Gong, Qiaoyun, Zhang, Jingting, Wang, Haiyan, Qiu, Qinghua, Zhang, Jingfa, Luo, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443035/
https://www.ncbi.nlm.nih.gov/pubmed/36064447
http://dx.doi.org/10.1186/s40662-022-00305-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443035/
https://www.ncbi.nlm.nih.gov/pubmed/36064447
http://dx.doi.org/10.1186/s40662-022-00305-2

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