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TRIM46 aggravated high glucose-induced hyper permeability and inflammatory response in human retinal capillary endothelial cells by promoting IκBα ubiquitination
BACKGROUND: Diabetic retinopathy (DR) as a severe diabetic complication contributes to blindness. The increased permeability of retinal capillary endothelial cells (RCECs) as well as the production of inflammatory markers are closely related to DR occurrence. We recently revealed that TRIM46 promote...
Autores principales: | Shen, Hangqi, Gong, Qiaoyun, Zhang, Jingting, Wang, Haiyan, Qiu, Qinghua, Zhang, Jingfa, Luo, Dawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443035/ https://www.ncbi.nlm.nih.gov/pubmed/36064447 http://dx.doi.org/10.1186/s40662-022-00305-2 |
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