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Protein O-GlcNAcylation and the regulation of energy homeostasis: lessons from knock-out mouse models

O-GlcNAcylation corresponds to the addition of N-Acetylglucosamine (GlcNAc) on serine or threonine residues of cytosolic, nuclear and mitochondrial proteins. This reversible modification is catalysed by a unique couple of enzymes, O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA). OGT uses UDP-GlcNAc...

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Detalles Bibliográficos
Autores principales: Issad, Tarik, Al-Mukh, Hasanain, Bouaboud, Abdelouhab, Pagesy, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443036/
https://www.ncbi.nlm.nih.gov/pubmed/36058931
http://dx.doi.org/10.1186/s12929-022-00851-w