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A versatile way for the synthesis of monomethylamines by reduction of N-substituted carbonylimidazoles with the NaBH(4)/I(2) system

An economical and versatile protocol for the one-pot synthesis of monomethylamines by reduction of N-substituted carbonylimidazoles with NaBH(4)/I(2) in THF at reflux temperature is described. This method used no special catalyst and various monomethylamines can be easily obtained in moderate to goo...

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Detalles Bibliográficos
Autores principales: Chen, Lin, Zhou, Xuan, Chen, Zhiyong, Wang, Changxu, Wang, Shunjie, Teng, Hanbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443423/
https://www.ncbi.nlm.nih.gov/pubmed/36105729
http://dx.doi.org/10.3762/bjoc.18.104