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Model-based intensification of CHO cell cultures: One-step strategy from fed-batch to perfusion

There is a growing interest in continuous processing of the biopharmaceutical industry. However, the technology transfer from traditional batch-based processes is considered a challenge as protocol and tools still remain to be established for their usage at the manufacturing scale. Here, we present...

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Detalles Bibliográficos
Autores principales: Richelle, Anne, Corbett, Brandon, Agarwal, Piyush, Vernersson, Anton, Trygg, Johan, McCready, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9443430/
https://www.ncbi.nlm.nih.gov/pubmed/36072286
http://dx.doi.org/10.3389/fbioe.2022.948905