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Tracking fibrosis in myeloproliferative neoplasms by CCR2 expression on CD34(+) cells

In myeloproliferative neoplasm (MPNs), bone marrow fibrosis - mainly driven by the neoplastic megakaryocytic clone - dictates a more severe disease stage with dismal prognosis and higher risk of leukemic evolution. Therefore, accurate patient allocation into different disease categories and timely i...

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Detalles Bibliográficos
Autores principales: Pozzi, Giulia, Carubbi, Cecilia, Gobbi, Giuliana, Tagliaferri, Sara, Mirandola, Prisco, Vitale, Marco, Masselli, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444005/
https://www.ncbi.nlm.nih.gov/pubmed/36072806
http://dx.doi.org/10.3389/fonc.2022.980379