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Tracking fibrosis in myeloproliferative neoplasms by CCR2 expression on CD34(+) cells
In myeloproliferative neoplasm (MPNs), bone marrow fibrosis - mainly driven by the neoplastic megakaryocytic clone - dictates a more severe disease stage with dismal prognosis and higher risk of leukemic evolution. Therefore, accurate patient allocation into different disease categories and timely i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444005/ https://www.ncbi.nlm.nih.gov/pubmed/36072806 http://dx.doi.org/10.3389/fonc.2022.980379 |