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Last but not least: BFL-1 as an emerging target for anti-cancer therapies

BFL-1 is an understudied pro-survival BCL-2 protein. The expression of BFL-1 is reported in many cancers, but it is yet to be clarified whether high transcript expression also always correlates with a pro-survival function. However, recent applications of BH3-mimetics for the treatment of blood canc...

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Detalles Bibliográficos
Autores principales: Wang, Gaoyuan, Diepstraten, Sarah T., Herold, Marco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444066/
https://www.ncbi.nlm.nih.gov/pubmed/35900226
http://dx.doi.org/10.1042/BST20220153