Focal adhesion kinase priming in pancreatic cancer, altering biomechanics to improve chemotherapy

The dense desmoplastic and fibrotic stroma is a characteristic feature of pancreatic ductal adenocarcinoma (PDAC), regulating disease progression, metastasis and response to treatment. Reciprocal interactions between the tumour and stroma are mediated by bidirectional integrin-mediated signalling, i...

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Detalles Bibliográficos
Autores principales: Murphy, Kendelle J., Zhu, Jessie, Trpceski, Michael, Pereira, Brooke A., Timpson, Paul, Herrmann, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444069/
https://www.ncbi.nlm.nih.gov/pubmed/35929603
http://dx.doi.org/10.1042/BST20220162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444069/
https://www.ncbi.nlm.nih.gov/pubmed/35929603
http://dx.doi.org/10.1042/BST20220162

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