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Two-pore channels: going with the flows

In recent years, our understanding of the structure, mechanisms and functions of the endo-lysosomal TPC (two-pore channel) family have grown apace. Gated by the second messengers, NAADP and PI(3,5)P(2), TPCs are an integral part of fundamental signal-transduction pathways, but their array and plasti...

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Detalles Bibliográficos
Autores principales: Morgan, Anthony J., Martucci, Lora L., Davis, Lianne C., Galione, Antony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444070/
https://www.ncbi.nlm.nih.gov/pubmed/35959977
http://dx.doi.org/10.1042/BST20220229