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Translational development of ABCB5(+) dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers

BACKGROUND: While rapid healing of diabetic foot ulcers (DFUs) is highly desirable to avoid infections, amputations and life-threatening complications, DFUs often respond poorly to standard treatment. GMP-manufactured skin-derived ABCB5(+) mesenchymal stem cells (MSCs) might provide a new adjunctive...

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Detalles Bibliográficos
Autores principales: Kerstan, Andreas, Dieter, Kathrin, Niebergall-Roth, Elke, Klingele, Sabrina, Jünger, Michael, Hasslacher, Christoph, Daeschlein, Georg, Stemler, Lutz, Meyer-Pannwitt, Ulrich, Schubert, Kristin, Klausmann, Gerhard, Raab, Titus, Goebeler, Matthias, Kraft, Korinna, Esterlechner, Jasmina, Schröder, Hannes M., Sadeghi, Samar, Ballikaya, Seda, Gasser, Martin, Waaga-Gasser, Ana M., Murphy, George F., Orgill, Dennis P., Frank, Natasha Y., Ganss, Christoph, Scharffetter-Kochanek, Karin, Frank, Markus H., Kluth, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9444095/
https://www.ncbi.nlm.nih.gov/pubmed/36064604
http://dx.doi.org/10.1186/s13287-022-03156-9